Oxidative stress is known as the main factor for the pathogenesis of neurodegenerative diseases. The present study aims at exploring the antioxidant and anticholinesterase activities of ethanolic turmeric crude extract. The ethanolic crude extract of turmeric showed antioxidant and anticholinesterase activities (% I) at 80.2±1.30 %, 75.6±1.23 % and 10.43±0.28 % for ABTS, DPPH and FRAP, respectively, and 69.0±1.85 % and 70.5±1.11 % for acetylcholinesterase and butyrylcholinesterase, respectively. However, the maximum % I for ABTS, DPPH and FRAP, that is, 87.2±1.34 %, 86.0±1.59 % and 19.36±0.37 µg FSE, respectively, was shown by positive control ascorbic acid, and for acetylcholinesterase and butyrylcholinesterase inhibition at 86.69±1.24 and 89.3±1.01 %, respectively, by galanthamine. Turmeric provide a potential natural source of bioactive compounds, and valuable to the human health.